[2025-09-25T11:13:34.429127] [QUERYOME] Starting research for query 92: 'Instructions: 
 Answer the question below. Please respond with the option letter (A, B, or C) first. (HINT: Each PubMedQA instance is composed of (1) a question which is either an existing research article title or derived from one, (2) a context which is the corresponding abstract without its conclusion, (3) a long answer, which is the conclusion of the abstract and, presumably, answers the research question, and (4) a yes/no/maybe answer which summarizes the conclusion.) 

Question:
Is the combination with 2-methoxyestradiol able to reduce the dosages of chemotherapeutices in the treatment of human ovarian cancer? 

Options:
{'A': 'yes', 'B': 'no', 'C': 'maybe'}'
[2025-09-25T11:13:34.516076] [PI] Starting research for query: 'Instructions: 
 Answer the question below. Please respond with the option letter (A, B, or C) first. (HINT: Each PubMedQA instance is composed of (1) a question which is either an existing research article title or derived from one, (2) a context which is the corresponding abstract without its conclusion, (3) a long answer, which is the conclusion of the abstract and, presumably, answers the research question, and (4) a yes/no/maybe answer which summarizes the conclusion.) 

Question:
Is the combination with 2-methoxyestradiol able to reduce the dosages of chemotherapeutices in the treatment of human ovarian cancer? 

Options:
{'A': 'yes', 'B': 'no', 'C': 'maybe'}'
[2025-09-25T11:13:34.518497] Saving text to bench_final/run1/pubmedqa/pubmedqa_91/pi_initial_prompt.txt
[2025-09-25T11:13:34.523457] [PI] Calling o3 for initial analysis...
[2025-09-25T11:13:39.819335] [PI] Reasoning iteration 1
[2025-09-25T11:13:39.821064] [PI] Executing function call 1: hybrid_search
[2025-09-25T11:13:39.823410] [PI] Function arguments: {'query': '2-methoxyestradiol combination reduce dosage of chemotherapeutic agents ovarian cancer', 'k': 10, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-25T11:13:39.824997] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_91/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-25T11:13:42.014813] [PI] Function hybrid_search executed successfully
[2025-09-25T11:13:42.018036] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_91/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-25T11:13:42.039720] [PI] Continuing reasoning with 1 function responses...
[2025-09-25T11:13:54.833992] [PI] Reasoning iteration 2
[2025-09-25T11:13:54.835654] [PI] No function calls found in response
[2025-09-25T11:13:54.838024] [PI] No more function calls - research complete
[2025-09-25T11:13:54.839739] Saving text to bench_final/run1/pubmedqa/pubmedqa_91/pi_final_answer.txt
[2025-09-25T11:13:54.844961] [QUERYOME] Query completed successfully
