[2025-09-25T11:04:46.833894] [QUERYOME] Starting research for query 67: 'Instructions: 
 Answer the question below. Please respond with the option letter (A, B, or C) first. (HINT: Each PubMedQA instance is composed of (1) a question which is either an existing research article title or derived from one, (2) a context which is the corresponding abstract without its conclusion, (3) a long answer, which is the conclusion of the abstract and, presumably, answers the research question, and (4) a yes/no/maybe answer which summarizes the conclusion.) 

Question:
Locoregional opening of the rodent blood-brain barrier for paclitaxel using Nd:YAG laser-induced thermo therapy: a new concept of adjuvant glioma therapy? 

Options:
{'A': 'yes', 'B': 'no', 'C': 'maybe'}'
[2025-09-25T11:04:46.930523] [PI] Starting research for query: 'Instructions: 
 Answer the question below. Please respond with the option letter (A, B, or C) first. (HINT: Each PubMedQA instance is composed of (1) a question which is either an existing research article title or derived from one, (2) a context which is the corresponding abstract without its conclusion, (3) a long answer, which is the conclusion of the abstract and, presumably, answers the research question, and (4) a yes/no/maybe answer which summarizes the conclusion.) 

Question:
Locoregional opening of the rodent blood-brain barrier for paclitaxel using Nd:YAG laser-induced thermo therapy: a new concept of adjuvant glioma therapy? 

Options:
{'A': 'yes', 'B': 'no', 'C': 'maybe'}'
[2025-09-25T11:04:46.933188] Saving text to bench_final/run1/pubmedqa/pubmedqa_66/pi_initial_prompt.txt
[2025-09-25T11:04:46.938379] [PI] Calling o3 for initial analysis...
[2025-09-25T11:04:50.118466] [PI] Reasoning iteration 1
[2025-09-25T11:04:50.120106] [PI] Executing function call 1: hybrid_search
[2025-09-25T11:04:50.123195] [PI] Function arguments: {'query': '"Locoregional opening of the rodent blood-brain barrier for paclitaxel using Nd:YAG laser-induced thermo therapy"', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-25T11:04:50.124797] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_66/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-25T11:04:51.698525] [PI] Function hybrid_search executed successfully
[2025-09-25T11:04:51.700637] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_66/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-25T11:04:51.715848] [PI] Continuing reasoning with 1 function responses...
[2025-09-25T11:04:55.035649] [PI] Reasoning iteration 2
[2025-09-25T11:04:55.038642] [PI] Executing function call 1: hybrid_search
[2025-09-25T11:04:55.040401] [PI] Function arguments: {'query': '12913878 abstract', 'k': 3, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-25T11:04:55.043271] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_66/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-09-25T11:04:55.867909] [PI] Function hybrid_search executed successfully
[2025-09-25T11:04:55.869541] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_66/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-09-25T11:04:55.875198] [PI] Continuing reasoning with 1 function responses...
[2025-09-25T11:05:07.793976] [PI] Reasoning iteration 3
[2025-09-25T11:05:07.795548] [PI] No function calls found in response
[2025-09-25T11:05:07.798673] [PI] No more function calls - research complete
[2025-09-25T11:05:07.800318] Saving text to bench_final/run1/pubmedqa/pubmedqa_66/pi_final_answer.txt
[2025-09-25T11:05:07.813913] [QUERYOME] Query completed successfully
