[2025-09-25T13:20:15.013825] [QUERYOME] Starting research for query 460: 'Instructions: 
 Answer the question below. Please respond with the option letter (A, B, or C) first. (HINT: Each PubMedQA instance is composed of (1) a question which is either an existing research article title or derived from one, (2) a context which is the corresponding abstract without its conclusion, (3) a long answer, which is the conclusion of the abstract and, presumably, answers the research question, and (4) a yes/no/maybe answer which summarizes the conclusion.) 

Question:
Major depression and alcohol use disorder in adolescence: Does comorbidity lead to poorer outcomes of depression? 

Options:
{'A': 'yes', 'B': 'no', 'C': 'maybe'}'
[2025-09-25T13:20:15.097618] [PI] Starting research for query: 'Instructions: 
 Answer the question below. Please respond with the option letter (A, B, or C) first. (HINT: Each PubMedQA instance is composed of (1) a question which is either an existing research article title or derived from one, (2) a context which is the corresponding abstract without its conclusion, (3) a long answer, which is the conclusion of the abstract and, presumably, answers the research question, and (4) a yes/no/maybe answer which summarizes the conclusion.) 

Question:
Major depression and alcohol use disorder in adolescence: Does comorbidity lead to poorer outcomes of depression? 

Options:
{'A': 'yes', 'B': 'no', 'C': 'maybe'}'
[2025-09-25T13:20:15.099405] Saving text to bench_final/run1/pubmedqa/pubmedqa_459/pi_initial_prompt.txt
[2025-09-25T13:20:15.113468] [PI] Calling o3 for initial analysis...
[2025-09-25T13:20:23.816565] [PI] Reasoning iteration 1
[2025-09-25T13:20:23.818106] [PI] Executing function call 1: hybrid_search
[2025-09-25T13:20:23.821153] [PI] Function arguments: {'query': 'Major depression and alcohol use disorder in adolescence comorbidity outcomes of depression', 'k': 10, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-25T13:20:23.822714] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_459/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-25T13:20:26.449488] [PI] Function hybrid_search executed successfully
[2025-09-25T13:20:26.452581] Saving JSON to bench_final/run1/pubmedqa/pubmedqa_459/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-25T13:20:26.463605] [PI] Continuing reasoning with 1 function responses...
[2025-09-25T13:20:41.632795] [PI] Reasoning iteration 2
[2025-09-25T13:20:41.634412] [PI] No function calls found in response
[2025-09-25T13:20:41.637200] [PI] No more function calls - research complete
[2025-09-25T13:20:41.638919] Saving text to bench_final/run1/pubmedqa/pubmedqa_459/pi_final_answer.txt
[2025-09-25T13:20:41.647715] [QUERYOME] Query completed successfully
