B

Large meta-analyses consistently show that the major cardiovascular risk factors have sex-specific relative effects. Diabetes mellitus raises the risk of myocardial infarction about 50 % more in women than in men [Huxley, 2006, PMID 16531581]. Current cigarette smoking also confers a higher relative risk in women (≈25 % greater) than in men [Huxley, 2011, PMID 21321296]. Conversely, elevated total cholesterol and hypertension tend to exert equal or slightly stronger effects in men than in women [Peters, 2018, PMID 29754332]. Taken together, these data indicate that lipids, blood pressure, diabetes and smoking do not confer equal myocardial infarction risk in the two sexes.