A

The study comparing affinity column-mediated immunoassay (ACMIA) with microparticle enzyme immunoassay (MEIA) for measuring tacrolimus in whole blood found a strong correlation (r = 0.84) and concluded that ACMIA is precise, requires no pretreatment, and is only minimally affected by hematologic or biochemical status, supporting its use as an alternative assay method [Ju et al., 2008, PMID 19100463].