[2025-09-30T20:59:18.246023] [QUERYOME] Starting research for query 893: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
All of the following can be used to decreased intraocular pressure in glaucoma except? 

Options:
{'A': 'Mannitol', 'B': 'Methazolamide', 'C': 'Clonidine', 'D': 'Dexamethasone'}'
[2025-09-30T20:59:18.326690] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
All of the following can be used to decreased intraocular pressure in glaucoma except? 

Options:
{'A': 'Mannitol', 'B': 'Methazolamide', 'C': 'Clonidine', 'D': 'Dexamethasone'}'
[2025-09-30T20:59:18.329362] Saving text to bench_final/run1/medmcqa/medmcqa_892/pi_initial_prompt.txt
[2025-09-30T20:59:18.335861] [PI] Calling o3 for initial analysis...
[2025-09-30T20:59:23.549223] [PI] Reasoning iteration 1
[2025-09-30T20:59:23.551961] [PI reasoning] **Answering glaucoma question**

I’m tackling an exam-style question about decreasing intraocular pressure in glaucoma. The options include Mannitol and Methazolamide, both of which reduce IOP. Clonidine may lower IOP, but it's not commonly used. Dexamethasone, a steroid, actually increases IOP, so that’s the answer. I need to support this with citations about steroid-induced glaucoma, mannitol, and carbonic anhydrase inhibitors. I think I'll perform quick searches to gather relevant articles for this.
[2025-09-30T20:59:23.556132] [PI] Executing function call 1: hybrid_search
[2025-09-30T20:59:23.557890] [PI] Function arguments: {'query': 'dexamethasone increases intraocular pressure steroid induced glaucoma', 'k': 5, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-09-30T20:59:23.562862] Saving JSON to bench_final/run1/medmcqa/medmcqa_892/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-30T21:00:32.258295] [PI] Function hybrid_search executed successfully
[2025-09-30T21:00:32.260753] Saving JSON to bench_final/run1/medmcqa/medmcqa_892/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-30T21:00:32.266440] [PI] Continuing reasoning with 1 function responses...
[2025-09-30T21:00:38.714136] [PI] Reasoning iteration 2
[2025-09-30T21:00:38.716392] [PI] Executing function call 1: hybrid_search
[2025-09-30T21:00:38.718114] [PI] Function arguments: {'query': 'mannitol decreases intraocular pressure glaucoma', 'k': 5, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-09-30T21:00:38.719721] Saving JSON to bench_final/run1/medmcqa/medmcqa_892/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-09-30T21:01:47.698268] [PI] Function hybrid_search executed successfully
[2025-09-30T21:01:47.709597] Saving JSON to bench_final/run1/medmcqa/medmcqa_892/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-09-30T21:01:47.716289] [PI] Continuing reasoning with 1 function responses...
[2025-09-30T21:01:52.212483] [PI] Reasoning iteration 3
[2025-09-30T21:01:52.214502] [PI] Executing function call 1: hybrid_search
[2025-09-30T21:01:52.217670] [PI] Function arguments: {'query': 'clonidine intraocular pressure decrease glaucoma', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-30T21:01:52.219643] Saving JSON to bench_final/run1/medmcqa/medmcqa_892/pi_iteration_3_tool_call_2_hybrid_search.json
[2025-09-30T21:02:42.687786] [PI] Function hybrid_search executed successfully
[2025-09-30T21:02:42.692351] Saving JSON to bench_final/run1/medmcqa/medmcqa_892/pi_iteration_3_tool_result_2_hybrid_search.json
[2025-09-30T21:02:42.726740] [PI] Continuing reasoning with 1 function responses...
[2025-09-30T21:02:49.822365] [PI] Reasoning iteration 4
[2025-09-30T21:02:49.823575] [PI] No function calls found in response
[2025-09-30T21:02:49.831515] [PI] No more function calls - research complete
[2025-09-30T21:02:49.833208] Saving text to bench_final/run1/medmcqa/medmcqa_892/pi_final_answer.txt
[2025-09-30T21:02:49.846112] [QUERYOME] Query completed successfully
