[2025-09-30T16:21:16.232667] [QUERYOME] Starting research for query 783: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
A patient is not responding even after undergoing multiple platelet transfusion. Which of the following will be the best treatment for him? 

Options:
{'A': 'Random platelet donor', 'B': 'Single platelet donor', 'C': 'HLA matched platelet', 'D': 'Irradiated platelets'}'
[2025-09-30T16:21:16.314596] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
A patient is not responding even after undergoing multiple platelet transfusion. Which of the following will be the best treatment for him? 

Options:
{'A': 'Random platelet donor', 'B': 'Single platelet donor', 'C': 'HLA matched platelet', 'D': 'Irradiated platelets'}'
[2025-09-30T16:21:16.321546] Saving text to bench_final/run1/medmcqa/medmcqa_782/pi_initial_prompt.txt
[2025-09-30T16:21:16.325417] [PI] Calling o3 for initial analysis...
[2025-09-30T16:21:24.113162] [PI] Reasoning iteration 1
[2025-09-30T16:21:24.114892] [PI] Executing function call 1: hybrid_search
[2025-09-30T16:21:24.119036] [PI] Function arguments: {'query': 'platelet transfusion refractoriness management HLA matched platelets', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-30T16:21:24.121854] Saving JSON to bench_final/run1/medmcqa/medmcqa_782/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-30T16:22:28.569710] [PI] Function hybrid_search executed successfully
[2025-09-30T16:22:28.572537] Saving JSON to bench_final/run1/medmcqa/medmcqa_782/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-30T16:22:28.591951] [PI] Continuing reasoning with 1 function responses...
[2025-09-30T16:22:33.663841] [PI] Reasoning iteration 2
[2025-09-30T16:22:33.667097] [PI] Executing function call 1: hybrid_search
[2025-09-30T16:22:33.668640] [PI] Function arguments: {'query': 'platelet refractoriness not responding to platelet transfusion best treatment HLA matched', 'k': 3, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-30T16:22:33.672205] Saving JSON to bench_final/run1/medmcqa/medmcqa_782/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-09-30T16:23:49.553780] [PI] Function hybrid_search executed successfully
[2025-09-30T16:23:49.566811] Saving JSON to bench_final/run1/medmcqa/medmcqa_782/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-09-30T16:23:49.572158] [PI] Continuing reasoning with 1 function responses...
[2025-09-30T16:23:58.951843] [PI] Reasoning iteration 3
[2025-09-30T16:23:58.953378] [PI] No function calls found in response
[2025-09-30T16:23:58.954883] [PI] No more function calls - research complete
[2025-09-30T16:23:58.958000] Saving text to bench_final/run1/medmcqa/medmcqa_782/pi_final_answer.txt
[2025-09-30T16:23:58.974508] [QUERYOME] Query completed successfully
