A

Alport syndrome classically presents in adolescence with the triad of progressive hematuria/renal disease, sensorineural hearing loss, and ocular abnormalities that can lead to blindness; it is often familial due to X-linked or autosomal inheritance, explaining the father’s similar history and the child’s early hypertension from renal involvement [Chavez, 2024, PMID 39004457; Jacobs, 1992, PMID 1495781].