[2025-09-30T12:23:48.751747] [QUERYOME] Starting research for query 695: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Sickle cell mutation is 

Options:
{'A': 'Point mutation', 'B': 'Selective mutation', 'C': 'Frame shift mutation', 'D': 'Nonsense mutation'}'
[2025-09-30T12:23:48.820742] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Sickle cell mutation is 

Options:
{'A': 'Point mutation', 'B': 'Selective mutation', 'C': 'Frame shift mutation', 'D': 'Nonsense mutation'}'
[2025-09-30T12:23:48.825853] Saving text to bench_final/run1/medmcqa/medmcqa_694/pi_initial_prompt.txt
[2025-09-30T12:23:48.830987] [PI] Calling o3 for initial analysis...
[2025-09-30T12:23:52.410741] [PI] Reasoning iteration 1
[2025-09-30T12:23:52.412408] [PI] No function calls found in response
[2025-09-30T12:23:52.415290] [PI] No more function calls - research complete
[2025-09-30T12:23:52.418201] Saving text to bench_final/run1/medmcqa/medmcqa_694/pi_final_answer.txt
[2025-09-30T12:23:52.428774] [QUERYOME] Query completed successfully
