[2025-09-30T06:00:25.422730] [QUERYOME] Starting research for query 520: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Which of the following vitamin is synthesized in vivo, in the body by humans? 

Options:
{'A': 'Niacin', 'B': 'Pantothenic acid', 'C': 'Cyanocobalamin', 'D': 'Folic acid'}'
[2025-09-30T06:00:25.520722] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Which of the following vitamin is synthesized in vivo, in the body by humans? 

Options:
{'A': 'Niacin', 'B': 'Pantothenic acid', 'C': 'Cyanocobalamin', 'D': 'Folic acid'}'
[2025-09-30T06:00:25.529413] Saving text to bench_final/run1/medmcqa/medmcqa_519/pi_initial_prompt.txt
[2025-09-30T06:00:25.535346] [PI] Calling o3 for initial analysis...
[2025-09-30T06:00:31.973414] [PI] Reasoning iteration 1
[2025-09-30T06:00:31.975128] [PI reasoning] **Identifying vitamin synthesis**

I need to choose which vitamin is synthesized in the human body. After thinking it through, Niacin (vitamin B3) can indeed be synthesized from tryptophan, though not in sufficient amounts to meet all needs. On the other hand, Pantothenic acid (vitamin B5) is essential and cannot be synthesized de novo by humans. Cyanocobalamin (vitamin B12) and Folic acid (vitamin B9) also can't be produced by our bodies. So, Niacin is the correct answer. I'll look for citations to back this up.
[2025-09-30T06:00:31.977672] [PI] Executing function call 1: hybrid_search
[2025-09-30T06:00:31.979422] [PI] Function arguments: {'query': 'niacin synthesized from tryptophan in humans requirement precursor', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-30T06:00:31.982260] Saving JSON to bench_final/run1/medmcqa/medmcqa_519/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-30T06:01:20.758346] [PI] Function hybrid_search executed successfully
[2025-09-30T06:01:20.760010] Saving JSON to bench_final/run1/medmcqa/medmcqa_519/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-30T06:01:20.766916] [PI] Continuing reasoning with 1 function responses...
[2025-09-30T06:01:29.517605] [PI] Reasoning iteration 2
[2025-09-30T06:01:29.519364] [PI] No function calls found in response
[2025-09-30T06:01:29.522187] [PI] No more function calls - research complete
[2025-09-30T06:01:29.523872] Saving text to bench_final/run1/medmcqa/medmcqa_519/pi_final_answer.txt
[2025-09-30T06:01:29.529339] [QUERYOME] Query completed successfully
