[2025-10-02T09:44:39.195728] [QUERYOME] Starting research for query 2533: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
An elderly female presented with blockade, nasal discharge, diplopia and facial swelling. On examination, there is blackish discharge from the nasal cavity with necrosis of nasal mucosa, facial skin and palate. There is fixation of the right globe. There is elevated blood sugar and urinary ketones are positive.Which of the following would be the medication to be used in this patient?

Options:
A. Amphotericin B
B. Itraconazole
C. Ketoconazole
D. Broad spectrum antibiotics'
[2025-10-02T09:44:39.238368] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
An elderly female presented with blockade, nasal discharge, diplopia and facial swelling. On examination, there is blackish discharge from the nasal cavity with necrosis of nasal mucosa, facial skin and palate. There is fixation of the right globe. There is elevated blood sugar and urinary ketones are positive.Which of the following would be the medication to be used in this patient?

Options:
A. Amphotericin B
B. Itraconazole
C. Ketoconazole
D. Broad spectrum antibiotics'
[2025-10-02T09:44:39.240238] Saving text to bench_final/run1/medmcqa/medmcqa_4093/pi_initial_prompt.txt
[2025-10-02T09:44:39.243625] [PI] Calling o3 for initial analysis...
[2025-10-02T09:44:42.577732] [PI] Reasoning iteration 1
[2025-10-02T09:44:42.579356] [PI] Executing function call 1: hybrid_search
[2025-10-02T09:44:42.581784] [PI] Function arguments: {'query': 'mucormycosis amphotericin B first line treatment rhinocerebral mucormycosis diabetic ketoacidosis nasal black eschar', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-02T09:44:42.583487] Saving JSON to bench_final/run1/medmcqa/medmcqa_4093/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-02T09:44:43.270953] [PI] Function hybrid_search executed successfully
[2025-10-02T09:44:43.275823] Saving JSON to bench_final/run1/medmcqa/medmcqa_4093/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-02T09:44:43.281477] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T09:44:49.646373] [PI] Reasoning iteration 2
[2025-10-02T09:44:49.647824] [PI] No function calls found in response
[2025-10-02T09:44:49.651511] [PI] No more function calls - research complete
[2025-10-02T09:44:49.653641] Saving text to bench_final/run1/medmcqa/medmcqa_4093/pi_final_answer.txt
[2025-10-02T09:44:49.658561] [QUERYOME] Query completed successfully
