C

Hand-foot-mouth disease from Coxsackie virus (especially A6/A16) can begin on the face and quickly produce vesiculobullous lesions on the hands, feet and other limbs in infants, matching the distribution in the photo [Feder et al., 2014, PMID 24287184]. HSV, HPV and congenital CMV do not typically cause this acute, widespread face-plus-extremity vesicular eruption, making Coxsackie the most likely pathogen.