[2025-10-02T06:40:14.346469] [QUERYOME] Starting research for query 2141: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
All of the following puy NiUiugiLai changes are seen in pregnancy except:

Options:
A. Increased stroke volume
B. Increased cardiac output
C. Increased intravascular volume
D. Increased peripheral resistance'
[2025-10-02T06:40:14.391664] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
All of the following puy NiUiugiLai changes are seen in pregnancy except:

Options:
A. Increased stroke volume
B. Increased cardiac output
C. Increased intravascular volume
D. Increased peripheral resistance'
[2025-10-02T06:40:14.393501] Saving text to bench_final/run1/medmcqa/medmcqa_3701/pi_initial_prompt.txt
[2025-10-02T06:40:14.413801] [PI] Calling o3 for initial analysis...
[2025-10-02T06:40:20.057985] [PI] Reasoning iteration 1
[2025-10-02T06:40:20.060500] [PI reasoning] **Interpreting changes in pregnancy**

I’m looking at a question about changes seen in pregnancy, specifically identifying which of the listed changes does not occur. It seems "puy NiUiugiLai changes" might actually refer to "physiological changes." During pregnancy, we know stroke volume and cardiac output increase, and intravascular volume increases, but peripheral resistance actually decreases. So, I think the option describing increased peripheral resistance is the correct answer. I'll also gather some evidence for support.
[2025-10-02T06:40:20.062306] [PI] Executing function call 1: hybrid_search
[2025-10-02T06:40:20.064093] [PI] Function arguments: {'query': 'pregnancy peripheral vascular resistance decreases systemic vascular resistance pregnancy stroke volume increases cardiac output increases intravascular volume pregnancy', 'k': 5, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-10-02T06:40:20.066547] Saving JSON to bench_final/run1/medmcqa/medmcqa_3701/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-02T06:40:20.870780] [PI] Function hybrid_search executed successfully
[2025-10-02T06:40:20.872510] Saving JSON to bench_final/run1/medmcqa/medmcqa_3701/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-02T06:40:20.878491] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T06:40:27.565873] [PI] Reasoning iteration 2
[2025-10-02T06:40:27.567269] [PI] No function calls found in response
[2025-10-02T06:40:27.568944] [PI] No more function calls - research complete
[2025-10-02T06:40:27.571268] Saving text to bench_final/run1/medmcqa/medmcqa_3701/pi_final_answer.txt
[2025-10-02T06:40:27.588241] [QUERYOME] Query completed successfully
