[2025-10-02T05:38:12.678760] [QUERYOME] Starting research for query 1998: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
Presented edema, oliguria and frothy urine. He has no past history of similar complaints. On examination, his urine was positive for 3+ proteinuria, no RBCs/WBCs and no casts. His serum albumin was 2.5 gm/L and serum creatinine was 0.5 mg/dL. The most likely diagnosis is:

Options:
A. Minimal change disease
B. IgA nephropathy
C. Interstitial nephritis
D. Membranous nephropathy'
[2025-10-02T05:38:12.720789] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
Presented edema, oliguria and frothy urine. He has no past history of similar complaints. On examination, his urine was positive for 3+ proteinuria, no RBCs/WBCs and no casts. His serum albumin was 2.5 gm/L and serum creatinine was 0.5 mg/dL. The most likely diagnosis is:

Options:
A. Minimal change disease
B. IgA nephropathy
C. Interstitial nephritis
D. Membranous nephropathy'
[2025-10-02T05:38:12.722407] Saving text to bench_final/run1/medmcqa/medmcqa_3558/pi_initial_prompt.txt
[2025-10-02T05:38:12.747014] [PI] Calling o3 for initial analysis...
[2025-10-02T05:38:19.410902] [PI] Reasoning iteration 1
[2025-10-02T05:38:19.412479] [PI] Executing function call 1: hybrid_search
[2025-10-02T05:38:19.415405] [PI] Function arguments: {'query': 'minimal change disease nephrotic syndrome proteinuria no hematuria low albumin children edema', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-02T05:38:19.417092] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-02T05:38:20.235608] [PI] Function hybrid_search executed successfully
[2025-10-02T05:38:20.237574] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-02T05:38:20.244006] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T05:38:23.444043] [PI] Reasoning iteration 2
[2025-10-02T05:38:23.446624] [PI] Executing function call 1: hybrid_search
[2025-10-02T05:38:23.448951] [PI] Function arguments: {'query': 'IgA nephropathy presentation hematuria proteinuria', 'k': 3, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-10-02T05:38:23.451665] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-10-02T05:38:24.309206] [PI] Function hybrid_search executed successfully
[2025-10-02T05:38:24.312719] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-10-02T05:38:24.322699] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T05:38:27.911770] [PI] Reasoning iteration 3
[2025-10-02T05:38:27.913457] [PI] Executing function call 1: hybrid_search
[2025-10-02T05:38:27.916311] [PI] Function arguments: {'query': 'membranous nephropathy nephrotic syndrome hematuria', 'k': 3, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-02T05:38:27.918431] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_3_tool_call_2_hybrid_search.json
[2025-10-02T05:38:28.845486] [PI] Function hybrid_search executed successfully
[2025-10-02T05:38:28.847213] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_3_tool_result_2_hybrid_search.json
[2025-10-02T05:38:28.853510] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T05:38:36.554876] [PI] Reasoning iteration 4
[2025-10-02T05:38:36.557204] [PI] Executing function call 1: hybrid_search
[2025-10-02T05:38:36.561041] [PI] Function arguments: {'query': 'minimal change disease no hematuria selective proteinuria', 'k': 5, 'faiss_weight': 0.7, 'bm25_weight': 0.3, 'use_rrf': True}
[2025-10-02T05:38:36.563302] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_4_tool_call_2_hybrid_search.json
[2025-10-02T05:38:37.250989] [PI] Function hybrid_search executed successfully
[2025-10-02T05:38:37.252818] Saving JSON to bench_final/run1/medmcqa/medmcqa_3558/pi_iteration_4_tool_result_2_hybrid_search.json
[2025-10-02T05:38:37.258823] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T05:38:44.862989] [PI] Reasoning iteration 5
[2025-10-02T05:38:44.865902] [PI] No function calls found in response
[2025-10-02T05:38:44.867751] [PI] No more function calls - research complete
[2025-10-02T05:38:44.870519] Saving text to bench_final/run1/medmcqa/medmcqa_3558/pi_final_answer.txt
[2025-10-02T05:38:44.875506] [QUERYOME] Query completed successfully
