[2025-10-02T03:38:51.031160] [QUERYOME] Starting research for query 1746: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
The case of biliary duct stricture with retching and vomiting, given 3mg morphine epiduraly daily, one day 12 mg mistakenly dose of epidural, morphine given. Not present:-

Options:
A. Itching
B. Urinary retention
C. Increase vomiting
D. Overstimulation of respiratory centre'
[2025-10-02T03:38:51.095135] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
The case of biliary duct stricture with retching and vomiting, given 3mg morphine epiduraly daily, one day 12 mg mistakenly dose of epidural, morphine given. Not present:-

Options:
A. Itching
B. Urinary retention
C. Increase vomiting
D. Overstimulation of respiratory centre'
[2025-10-02T03:38:51.096794] Saving text to bench_final/run1/medmcqa/medmcqa_3306/pi_initial_prompt.txt
[2025-10-02T03:38:51.107926] [PI] Calling o3 for initial analysis...
[2025-10-02T03:38:57.636673] [PI] Reasoning iteration 1
[2025-10-02T03:38:57.638263] [PI reasoning] **Assessing morphine overdose effects**

I need to tackle a multiple-choice question about the effects of epidural morphine overdose, specifically identifying which effect is NOT present. Given the scenario—a patient with biliary duct stricture who received a mistakenly high dose of morphine daily—my options are A) itching, B) urinary retention, C) increased vomiting, and D) overstimulation of the respiratory center. Clearly, I can rule out D, as morphine depresses rather than stimulates the respiratory center. Let's confirm the side effects quickly!
[2025-10-02T03:38:57.640017] [PI] Executing function call 1: hybrid_search
[2025-10-02T03:38:57.641372] [PI] Function arguments: {'query': 'epidural morphine side effects pruritus urinary retention nausea vomiting respiratory depression', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-02T03:38:57.643009] Saving JSON to bench_final/run1/medmcqa/medmcqa_3306/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-02T03:38:58.215372] [PI] Function hybrid_search executed successfully
[2025-10-02T03:38:58.217677] Saving JSON to bench_final/run1/medmcqa/medmcqa_3306/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-02T03:38:58.235068] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T03:39:01.268870] [PI] Reasoning iteration 2
[2025-10-02T03:39:01.271761] [PI] No function calls found in response
[2025-10-02T03:39:01.273404] [PI] No more function calls - research complete
[2025-10-02T03:39:01.275791] Saving text to bench_final/run1/medmcqa/medmcqa_3306/pi_final_answer.txt
[2025-10-02T03:39:01.280614] [QUERYOME] Query completed successfully
