[2025-09-29T23:14:31.540378] [QUERYOME] Starting research for query 324: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Which is not associated with GDM (Gestational DM)? 

Options:
{'A': 'Past history of fetal abnormality', 'B': 'Obesity', 'C': 'Hypeension', 'D': 'Macrosomia'}'
[2025-09-29T23:14:31.596728] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Which is not associated with GDM (Gestational DM)? 

Options:
{'A': 'Past history of fetal abnormality', 'B': 'Obesity', 'C': 'Hypeension', 'D': 'Macrosomia'}'
[2025-09-29T23:14:31.605124] Saving text to bench_final/run1/medmcqa/medmcqa_323/pi_initial_prompt.txt
[2025-09-29T23:14:31.609272] [PI] Calling o3 for initial analysis...
[2025-09-29T23:14:40.345257] [PI] Reasoning iteration 1
[2025-09-29T23:14:40.347791] [PI reasoning] **Clarifying GDM associations**

I'm working through a multiple-choice question about gestational diabetes mellitus (GDM) and its risk factors. I know GDM is typically linked with obesity, hypertension, and previous large infants. Interestingly, while I thought previous congenital malformations might be relevant, it seems that's less common. The known risk factors include age over 25, obesity, or previous GDM. I’m considering that "Past history of fetal abnormality" is likely not a direct risk factor for GDM. I should quickly verify this.
[2025-09-29T23:14:40.350699] [PI] Executing function call 1: bm25_author_keywords_search
[2025-09-29T23:14:40.352366] [PI] Function arguments: {'query': 'gestational diabetes risk factors previous fetal abnormality congenital malformation', 'k': 10}
[2025-09-29T23:14:40.354634] Saving JSON to bench_final/run1/medmcqa/medmcqa_323/pi_iteration_1_tool_call_2_bm25_author_keywords_search.json
[2025-09-29T23:14:41.350196] [PI] Function bm25_author_keywords_search executed successfully
[2025-09-29T23:14:41.352212] Saving JSON to bench_final/run1/medmcqa/medmcqa_323/pi_iteration_1_tool_result_2_bm25_author_keywords_search.json
[2025-09-29T23:14:41.378451] [PI] Continuing reasoning with 1 function responses...
[2025-09-29T23:14:48.738912] [PI] Reasoning iteration 2
[2025-09-29T23:14:48.740537] [PI reasoning] **Exploring GDM risk factors**

I’ve noticed that my search results aren’t providing the risk factors for gestational diabetes mellitus (GDM). Maybe I could try searching for terms focusing on "gestational diabetes mellitus risk factors" combined with "fetal abnormality history." Conceptually, I know GDM is linked to outcomes like fetal congenital malformations, especially if hyperglycemic early on, but maternal GDM generally gets diagnosed during mid-pregnancy, leading to lower risks. Factors like obesity and hypertension are risks, but a previous fetal abnormality isn’t. I’ll gather evidence quickly with a new search focused on those risk factors.
[2025-09-29T23:14:48.742172] [PI] Executing function call 1: hybrid_search
[2025-09-29T23:14:48.744224] [PI] Function arguments: {'query': 'gestational diabetes risk factors obesity hypertension macrosomia', 'k': 10, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-09-29T23:14:48.745852] Saving JSON to bench_final/run1/medmcqa/medmcqa_323/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-09-29T23:15:34.246594] [PI] Function hybrid_search executed successfully
[2025-09-29T23:15:34.248333] Saving JSON to bench_final/run1/medmcqa/medmcqa_323/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-09-29T23:15:34.253621] [PI] Continuing reasoning with 1 function responses...
[2025-09-29T23:15:44.555018] [PI] Reasoning iteration 3
[2025-09-29T23:15:44.557551] [PI] No function calls found in response
[2025-09-29T23:15:44.559890] [PI] No more function calls - research complete
[2025-09-29T23:15:44.561480] Saving text to bench_final/run1/medmcqa/medmcqa_323/pi_final_answer.txt
[2025-09-29T23:15:44.565377] [QUERYOME] Query completed successfully
