[2025-10-02T02:59:17.592060] [QUERYOME] Starting research for query 1661: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
Vasopressor of choice in pregnancy is:

Options:
A. Ephedrine
B. Phenylephrine
C. Methoxamine
D. Mephentermine'
[2025-10-02T02:59:17.646807] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
Vasopressor of choice in pregnancy is:

Options:
A. Ephedrine
B. Phenylephrine
C. Methoxamine
D. Mephentermine'
[2025-10-02T02:59:17.648577] Saving text to bench_final/run1/medmcqa/medmcqa_3221/pi_initial_prompt.txt
[2025-10-02T02:59:17.653174] [PI] Calling o3 for initial analysis...
[2025-10-02T02:59:29.666555] [PI] Reasoning iteration 1
[2025-10-02T02:59:29.668338] [PI reasoning] **Evaluating vasopressor options**

I need to address the question about the vasopressor of choice during pregnancy, especially in the context of maternal hypotension and spinal anesthesia for cesarean sections. Historically, ephedrine has been regarded as the first choice due to its favorable uteroplacental blood flow. However, recent evidence suggests that phenylephrine might actually be superior, as it maintains blood pressure with less risk of fetal acidosis. This question likely pertains to specific Indian exams, where older texts still favor ephedrine. It's crucial to clarify which exam this refers to.
[2025-10-02T02:59:29.671107] [PI] Executing function call 1: hybrid_search
[2025-10-02T02:59:29.673057] [PI] Function arguments: {'query': 'phenylephrine vasopressor of choice in pregnancy hypotension cesarean', 'k': 10, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-02T02:59:29.675636] Saving JSON to bench_final/run1/medmcqa/medmcqa_3221/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-02T02:59:30.445555] [PI] Function hybrid_search executed successfully
[2025-10-02T02:59:30.447551] Saving JSON to bench_final/run1/medmcqa/medmcqa_3221/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-02T02:59:30.455424] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T02:59:33.032293] [PI] Reasoning iteration 2
[2025-10-02T02:59:33.034971] [PI] Executing function call 1: hybrid_search
[2025-10-02T02:59:33.036675] [PI] Function arguments: {'query': 'vasopressor of choice in obstetric patients ephedrine', 'k': 10, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-02T02:59:33.038465] Saving JSON to bench_final/run1/medmcqa/medmcqa_3221/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-10-02T02:59:34.052571] [PI] Function hybrid_search executed successfully
[2025-10-02T02:59:34.055281] Saving JSON to bench_final/run1/medmcqa/medmcqa_3221/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-10-02T02:59:34.060690] [PI] Continuing reasoning with 1 function responses...
[2025-10-02T02:59:40.763401] [PI] Reasoning iteration 3
[2025-10-02T02:59:40.766015] [PI] No function calls found in response
[2025-10-02T02:59:40.767550] [PI] No more function calls - research complete
[2025-10-02T02:59:40.770051] Saving text to bench_final/run1/medmcqa/medmcqa_3221/pi_final_answer.txt
[2025-10-02T02:59:40.790505] [QUERYOME] Query completed successfully
