[2025-09-29T20:46:41.321190] [QUERYOME] Starting research for query 252: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Major mechanism of transport of drugs across biological membranes is by ? 

Options:
{'A': 'Passive diffusion', 'B': 'Facilitated diffusion', 'C': 'Active transport', 'D': 'Endocytosis'}'
[2025-09-29T20:46:41.372696] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Major mechanism of transport of drugs across biological membranes is by ? 

Options:
{'A': 'Passive diffusion', 'B': 'Facilitated diffusion', 'C': 'Active transport', 'D': 'Endocytosis'}'
[2025-09-29T20:46:41.374250] Saving text to bench_final/run1/medmcqa/medmcqa_251/pi_initial_prompt.txt
[2025-09-29T20:46:41.387486] [PI] Calling o3 for initial analysis...
[2025-09-29T20:46:45.643136] [PI] Reasoning iteration 1
[2025-09-29T20:46:45.644919] [PI] Executing function call 1: hybrid_search
[2025-09-29T20:46:45.647866] [PI] Function arguments: {'query': 'major mechanism of drug transport across biological membranes is passive diffusion', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-29T20:46:45.649572] Saving JSON to bench_final/run1/medmcqa/medmcqa_251/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-29T20:47:14.189211] [PI] Function hybrid_search executed successfully
[2025-09-29T20:47:14.190944] Saving JSON to bench_final/run1/medmcqa/medmcqa_251/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-29T20:47:14.198595] [PI] Continuing reasoning with 1 function responses...
[2025-09-29T20:47:21.228423] [PI] Reasoning iteration 2
[2025-09-29T20:47:21.233728] [PI] No function calls found in response
[2025-09-29T20:47:21.235496] [PI] No more function calls - research complete
[2025-09-29T20:47:21.238694] Saving text to bench_final/run1/medmcqa/medmcqa_251/pi_final_answer.txt
[2025-09-29T20:47:21.249199] [QUERYOME] Query completed successfully
