[2025-09-29T20:46:01.533618] [QUERYOME] Starting research for query 251: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Pegloticase used in which of the following conditions? 

Options:
{'A': 'Chronic Gout', 'B': 'Psoriatic ahritis', 'C': 'RA', 'D': 'Paralytic Ileus'}'
[2025-09-29T20:46:01.593184] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Pegloticase used in which of the following conditions? 

Options:
{'A': 'Chronic Gout', 'B': 'Psoriatic ahritis', 'C': 'RA', 'D': 'Paralytic Ileus'}'
[2025-09-29T20:46:01.594914] Saving text to bench_final/run1/medmcqa/medmcqa_250/pi_initial_prompt.txt
[2025-09-29T20:46:01.600213] [PI] Calling o3 for initial analysis...
[2025-09-29T20:46:04.935538] [PI] Reasoning iteration 1
[2025-09-29T20:46:04.937999] [PI] Executing function call 1: hybrid_search
[2025-09-29T20:46:04.939575] [PI] Function arguments: {'query': 'pegloticase chronic refractory gout treatment recombinant uricase FDA approval', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-09-29T20:46:04.941375] Saving JSON to bench_final/run1/medmcqa/medmcqa_250/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-09-29T20:46:38.687762] [PI] Function hybrid_search executed successfully
[2025-09-29T20:46:38.689960] Saving JSON to bench_final/run1/medmcqa/medmcqa_250/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-09-29T20:46:38.698271] [PI] Continuing reasoning with 1 function responses...
[2025-09-29T20:46:41.295025] [PI] Reasoning iteration 2
[2025-09-29T20:46:41.296593] [PI] No function calls found in response
[2025-09-29T20:46:41.298819] [PI] No more function calls - research complete
[2025-09-29T20:46:41.299936] Saving text to bench_final/run1/medmcqa/medmcqa_250/pi_final_answer.txt
[2025-09-29T20:46:41.317643] [QUERYOME] Query completed successfully
