[2025-10-01T20:32:56.581584] [QUERYOME] Starting research for query 770: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
All are Gp lIbilIla inhibitors except:

Options:
A. Prasugrel
B. Abciximab
C. Tirofiban
D. Eptifibatide'
[2025-10-01T20:32:56.622040] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
All are Gp lIbilIla inhibitors except:

Options:
A. Prasugrel
B. Abciximab
C. Tirofiban
D. Eptifibatide'
[2025-10-01T20:32:56.623881] Saving text to bench_final/run1/medmcqa/medmcqa_2330/pi_initial_prompt.txt
[2025-10-01T20:32:56.627960] [PI] Calling o3 for initial analysis...
[2025-10-01T20:33:01.577830] [PI] Reasoning iteration 1
[2025-10-01T20:33:01.581383] [PI reasoning] **Identifying inhibitors**

I need to determine which option isn’t a GP IIb/IIIa inhibitor. Abciximab, Tirofiban, and Eptifibatide are all GP IIb/IIIa inhibitors, but Prasugrel is different; it’s a thienopyridine P2Y12 receptor inhibitor, making it the correct answer. I should back this up with reasoning and some quick references to clarify. Clearly explaining this distinction will be crucial. Let’s gather the necessary citations soon!
[2025-10-01T20:33:01.583523] [PI] Executing function call 1: hybrid_search
[2025-10-01T20:33:01.586091] [PI] Function arguments: {'query': 'Prasugrel mechanism of action P2Y12 not GP IIb IIIa inhibitor', 'k': 5, 'faiss_weight': 0.7, 'bm25_weight': 0.3, 'use_rrf': True}
[2025-10-01T20:33:01.587871] Saving JSON to bench_final/run1/medmcqa/medmcqa_2330/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-01T20:33:02.761434] [PI] Function hybrid_search executed successfully
[2025-10-01T20:33:02.763073] Saving JSON to bench_final/run1/medmcqa/medmcqa_2330/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-01T20:33:02.787874] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T20:33:06.393579] [PI] Reasoning iteration 2
[2025-10-01T20:33:06.394662] [PI] Executing function call 1: hybrid_search
[2025-10-01T20:33:06.398894] [PI] Function arguments: {'query': 'Abciximab glycoprotein IIb IIIa inhibitor', 'k': 5, 'faiss_weight': 0.7, 'bm25_weight': 0.3, 'use_rrf': True}
[2025-10-01T20:33:06.411679] Saving JSON to bench_final/run1/medmcqa/medmcqa_2330/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-10-01T20:33:07.412366] [PI] Function hybrid_search executed successfully
[2025-10-01T20:33:07.413776] Saving JSON to bench_final/run1/medmcqa/medmcqa_2330/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-10-01T20:33:07.419285] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T20:33:12.891544] [PI] Reasoning iteration 3
[2025-10-01T20:33:12.893101] [PI] No function calls found in response
[2025-10-01T20:33:12.894826] [PI] No more function calls - research complete
[2025-10-01T20:33:12.897475] Saving text to bench_final/run1/medmcqa/medmcqa_2330/pi_final_answer.txt
[2025-10-01T20:33:12.917828] [QUERYOME] Query completed successfully
