[2025-10-01T19:36:25.970307] [QUERYOME] Starting research for query 632: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
In noncompetitive antagonism, the true statement is:

Options:
A. Km value decrease;.vmaxdecreases
B. no change in vmax;Km value decrease
C. V max decreased; Km value normal
D. Km value increased; V max increased'
[2025-10-01T19:36:26.032502] [PI] Starting research for query: 'Instructions:
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer.

Question:
In noncompetitive antagonism, the true statement is:

Options:
A. Km value decrease;.vmaxdecreases
B. no change in vmax;Km value decrease
C. V max decreased; Km value normal
D. Km value increased; V max increased'
[2025-10-01T19:36:26.034055] Saving text to bench_final/run1/medmcqa/medmcqa_2192/pi_initial_prompt.txt
[2025-10-01T19:36:26.039463] [PI] Calling o3 for initial analysis...
[2025-10-01T19:36:29.921630] [PI] Reasoning iteration 1
[2025-10-01T19:36:29.927517] [PI] Executing function call 1: hybrid_search
[2025-10-01T19:36:29.929601] [PI] Function arguments: {'query': 'noncompetitive inhibition decreases Vmax Km unchanged', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-01T19:36:29.932759] Saving JSON to bench_final/run1/medmcqa/medmcqa_2192/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-01T19:36:31.075031] [PI] Function hybrid_search executed successfully
[2025-10-01T19:36:31.077601] Saving JSON to bench_final/run1/medmcqa/medmcqa_2192/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-01T19:36:31.083336] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T19:36:39.738443] [PI] Reasoning iteration 2
[2025-10-01T19:36:39.741550] [PI] No function calls found in response
[2025-10-01T19:36:39.742898] [PI] No more function calls - research complete
[2025-10-01T19:36:39.744875] Saving text to bench_final/run1/medmcqa/medmcqa_2192/pi_final_answer.txt
[2025-10-01T19:36:39.749879] [QUERYOME] Query completed successfully
