D

Pemphigus vulgaris is characterized by IgG auto-antibodies against desmoglein-3 (and often desmoglein-1), the desmosomal “intercellular cement” that binds adjacent keratinocytes in stratified squamous epithelium; these circulating antibodies produce acantholysis and intra-epidermal blisters, a feature not seen in the other listed disorders [Ding 1999, PMID 10233765; Stanley 1995, PMID 7587627].