D

Mannitol (osmotic diuretic), topical/systemic carbonic-anhydrase inhibitors, and the α2-agonist apraclonidine are all established therapies that acutely lower intraocular pressure. In contrast, corticosteroids such as dexamethasone are well known to cause steroid-induced ocular hypertension and can precipitate or worsen glaucoma rather than relieve it, so they are not used to lower IOP [Lee, 2013, PMID 23326185; Malclès, 2017, PMID 27768641].