B

Glucagon raises intracellular cAMP in adipocytes, activating protein-kinase A, which phosphorylates and stimulates hormone-sensitive lipase to initiate lipolysis; lipoprotein and digestive lipases are regulated by other mechanisms, not by glucagon [Perea et al., 1995, PMID 7590626; Brasaemle et al., 2000, PMID 10634941].