[2025-10-01T06:40:28.183673] [QUERYOME] Starting research for query 1264: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Which is gametocidal for all species: 

Options:
{'A': 'Quinine', 'B': 'Chloroquine', 'C': 'Primaquine', 'D': 'None'}'
[2025-10-01T06:40:28.242736] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Which is gametocidal for all species: 

Options:
{'A': 'Quinine', 'B': 'Chloroquine', 'C': 'Primaquine', 'D': 'None'}'
[2025-10-01T06:40:28.244596] Saving text to bench_final/run1/medmcqa/medmcqa_1263/pi_initial_prompt.txt
[2025-10-01T06:40:28.255796] [PI] Calling o3 for initial analysis...
[2025-10-01T06:40:32.479717] [PI] Reasoning iteration 1
[2025-10-01T06:40:32.482663] [PI] Executing function call 1: hybrid_search
[2025-10-01T06:40:32.484567] [PI] Function arguments: {'query': 'Primaquine gametocidal against all plasmodium species mature gametocytes', 'k': 5, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-10-01T06:40:32.487594] Saving JSON to bench_final/run1/medmcqa/medmcqa_1263/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-01T06:40:35.068087] [PI] Function hybrid_search executed successfully
[2025-10-01T06:40:35.069683] Saving JSON to bench_final/run1/medmcqa/medmcqa_1263/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-01T06:40:35.090575] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T06:40:38.413710] [PI] Reasoning iteration 2
[2025-10-01T06:40:38.415324] [PI] Executing function call 1: hybrid_search
[2025-10-01T06:40:38.418013] [PI] Function arguments: {'query': 'Which antimalarial drug is gametocytocidal for all Plasmodium species primaquine', 'k': 10, 'faiss_weight': 0.3, 'bm25_weight': 0.7, 'use_rrf': True}
[2025-10-01T06:40:38.420126] Saving JSON to bench_final/run1/medmcqa/medmcqa_1263/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-10-01T06:41:05.395707] [PI] Function hybrid_search executed successfully
[2025-10-01T06:41:05.399462] Saving JSON to bench_final/run1/medmcqa/medmcqa_1263/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-10-01T06:41:05.418440] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T06:41:13.413399] [PI] Reasoning iteration 3
[2025-10-01T06:41:13.415240] [PI] No function calls found in response
[2025-10-01T06:41:13.418659] [PI] No more function calls - research complete
[2025-10-01T06:41:13.420362] Saving text to bench_final/run1/medmcqa/medmcqa_1263/pi_final_answer.txt
[2025-10-01T06:41:13.428438] [QUERYOME] Query completed successfully
