[2025-10-01T06:11:05.220694] [QUERYOME] Starting research for query 1240: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Sickle cell anemia is a - 

Options:
{'A': 'Gene deletion', 'B': 'Gene modification', 'C': 'Point mutation', 'D': 'Frame shift mutation'}'
[2025-10-01T06:11:05.273688] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
Sickle cell anemia is a - 

Options:
{'A': 'Gene deletion', 'B': 'Gene modification', 'C': 'Point mutation', 'D': 'Frame shift mutation'}'
[2025-10-01T06:11:05.276399] Saving text to bench_final/run1/medmcqa/medmcqa_1239/pi_initial_prompt.txt
[2025-10-01T06:11:05.281650] [PI] Calling o3 for initial analysis...
[2025-10-01T06:11:07.918567] [PI] Reasoning iteration 1
[2025-10-01T06:11:07.921484] [PI] Executing function call 1: hybrid_search
[2025-10-01T06:11:07.923321] [PI] Function arguments: {'query': 'sickle cell anemia point mutation substitution valine for glutamic acid beta globin gene', 'k': 5, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-01T06:11:07.925744] Saving JSON to bench_final/run1/medmcqa/medmcqa_1239/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-01T06:11:34.024374] [PI] Function hybrid_search executed successfully
[2025-10-01T06:11:34.027096] Saving JSON to bench_final/run1/medmcqa/medmcqa_1239/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-01T06:11:34.054965] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T06:11:38.242460] [PI] Reasoning iteration 2
[2025-10-01T06:11:38.244243] [PI] No function calls found in response
[2025-10-01T06:11:38.247509] [PI] No more function calls - research complete
[2025-10-01T06:11:38.249296] Saving text to bench_final/run1/medmcqa/medmcqa_1239/pi_final_answer.txt
[2025-10-01T06:11:38.256981] [QUERYOME] Query completed successfully
