[2025-10-01T02:35:31.422880] [QUERYOME] Starting research for query 1068: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
In a patient with heart disease, which of the following should not be used to control PPH: 

Options:
{'A': 'Methylergometrine', 'B': 'Oxytocin', 'C': 'Misoprostol', 'D': 'Carboprost'}'
[2025-10-01T02:35:31.478794] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
In a patient with heart disease, which of the following should not be used to control PPH: 

Options:
{'A': 'Methylergometrine', 'B': 'Oxytocin', 'C': 'Misoprostol', 'D': 'Carboprost'}'
[2025-10-01T02:35:31.483077] Saving text to bench_final/run1/medmcqa/medmcqa_1067/pi_initial_prompt.txt
[2025-10-01T02:35:31.502282] [PI] Calling o3 for initial analysis...
[2025-10-01T02:35:37.533517] [PI] Reasoning iteration 1
[2025-10-01T02:35:37.536035] [PI reasoning] **Considering uterotonic agents**

I’m exploring uterotonic agents for postpartum hemorrhage in a patient with heart disease. Methylergometrine is definitely contraindicated because it can worsen hypertension and cause coronary vasospasm. Carboprost may also cause hypertension and bronchospasm, mainly concerning for asthma. Misoprostol is safe, and while oxytocin can cause hypotension, it’s generally used. So, it seems Methylergometrine is the best choice to rule out. Now I’ll search for evidence on contraindications related to heart disease.
[2025-10-01T02:35:37.537723] [PI] Executing function call 1: hybrid_search
[2025-10-01T02:35:37.540576] [PI] Function arguments: {'query': 'methylergometrine contraindicated heart disease postpartum hemorrhage coronary vasospasm', 'k': 10, 'faiss_weight': 0.6, 'bm25_weight': 0.4, 'use_rrf': True}
[2025-10-01T02:35:37.542333] Saving JSON to bench_final/run1/medmcqa/medmcqa_1067/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-01T02:35:49.118109] [PI] Function hybrid_search executed successfully
[2025-10-01T02:35:49.131857] Saving JSON to bench_final/run1/medmcqa/medmcqa_1067/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-01T02:35:49.147983] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T02:35:58.038218] [PI] Reasoning iteration 2
[2025-10-01T02:35:58.040804] [PI] Executing function call 1: hybrid_search
[2025-10-01T02:35:58.042633] [PI] Function arguments: {'query': 'ergometrine contraindicated in heart disease postpartum hemorrhage guideline', 'k': 10, 'faiss_weight': 0.4, 'bm25_weight': 0.6, 'use_rrf': True}
[2025-10-01T02:35:58.044996] Saving JSON to bench_final/run1/medmcqa/medmcqa_1067/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-10-01T02:36:17.903559] [PI] Function hybrid_search executed successfully
[2025-10-01T02:36:17.906360] Saving JSON to bench_final/run1/medmcqa/medmcqa_1067/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-10-01T02:36:17.936240] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T02:36:23.706296] [PI] Reasoning iteration 3
[2025-10-01T02:36:23.707987] [PI] No function calls found in response
[2025-10-01T02:36:23.718718] [PI] No more function calls - research complete
[2025-10-01T02:36:23.721515] Saving text to bench_final/run1/medmcqa/medmcqa_1067/pi_final_answer.txt
[2025-10-01T02:36:23.725990] [QUERYOME] Query completed successfully
