[2025-10-01T02:27:50.077783] [QUERYOME] Starting research for query 1061: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
What is the dose of adrenaline in anaphylactic shock? 

Options:
{'A': '0.5 ml in 1:1000', 'B': '0.5 ml in 1:10000', 'C': '1 ml in 1:1000', 'D': '1.5 ml in 1:1000'}'
[2025-10-01T02:27:50.137880] [PI] Starting research for query: 'Instructions: 
 Answer the question below. First, respond with the single best option letter (A, B, C, or D). Then provide a concise reasoning (1–3 sentences). Use both the retrieved evidence and your own medical knowledge to choose the most accurate answer. 

Question:
What is the dose of adrenaline in anaphylactic shock? 

Options:
{'A': '0.5 ml in 1:1000', 'B': '0.5 ml in 1:10000', 'C': '1 ml in 1:1000', 'D': '1.5 ml in 1:1000'}'
[2025-10-01T02:27:50.140863] Saving text to bench_final/run1/medmcqa/medmcqa_1060/pi_initial_prompt.txt
[2025-10-01T02:27:50.146547] [PI] Calling o3 for initial analysis...
[2025-10-01T02:27:56.229234] [PI] Reasoning iteration 1
[2025-10-01T02:27:56.230797] [PI reasoning] **Determining adrenaline dosage**

I need to clarify the appropriate dose of adrenaline for anaphylactic shock. The standard adult dose is 0.5 mg administered intramuscularly, which translates to 0.5 mL of a 1:1000 solution. Therefore, I conclude that the answer is option A, which states '0.5 mL in 1:1000.' To back this up, I'll reference credible guidelines from sources like the World Allergy Organization or Resuscitation Council UK and look for relevant evidence on PubMed.
[2025-10-01T02:27:56.232785] [PI] Executing function call 1: hybrid_search
[2025-10-01T02:27:56.235764] [PI] Function arguments: {'query': 'intramuscular adrenaline dose anaphylaxis 0.5 mg 1:1000', 'k': 5, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-10-01T02:27:56.237250] Saving JSON to bench_final/run1/medmcqa/medmcqa_1060/pi_iteration_1_tool_call_2_hybrid_search.json
[2025-10-01T02:28:28.529439] [PI] Function hybrid_search executed successfully
[2025-10-01T02:28:28.531426] Saving JSON to bench_final/run1/medmcqa/medmcqa_1060/pi_iteration_1_tool_result_2_hybrid_search.json
[2025-10-01T02:28:28.537136] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T02:28:32.671682] [PI] Reasoning iteration 2
[2025-10-01T02:28:32.675183] [PI] Executing function call 1: hybrid_search
[2025-10-01T02:28:32.677392] [PI] Function arguments: {'query': 'Resuscitation Council UK 0.5 ml 1:1000 adrenaline anaphylaxis', 'k': 5, 'faiss_weight': 0.4, 'bm25_weight': 0.6, 'use_rrf': True}
[2025-10-01T02:28:32.680326] Saving JSON to bench_final/run1/medmcqa/medmcqa_1060/pi_iteration_2_tool_call_2_hybrid_search.json
[2025-10-01T02:29:03.420354] [PI] Function hybrid_search executed successfully
[2025-10-01T02:29:03.421904] Saving JSON to bench_final/run1/medmcqa/medmcqa_1060/pi_iteration_2_tool_result_2_hybrid_search.json
[2025-10-01T02:29:03.427092] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T02:29:07.832951] [PI] Reasoning iteration 3
[2025-10-01T02:29:07.835534] [PI] Executing function call 1: hybrid_search
[2025-10-01T02:29:07.837099] [PI] Function arguments: {'query': '0.5 ml of 1:1000 epinephrine intramuscular anaphylaxis adult', 'k': 10, 'faiss_weight': 0.5, 'bm25_weight': 0.5, 'use_rrf': True}
[2025-10-01T02:29:07.839793] Saving JSON to bench_final/run1/medmcqa/medmcqa_1060/pi_iteration_3_tool_call_2_hybrid_search.json
[2025-10-01T02:29:44.125610] [PI] Function hybrid_search executed successfully
[2025-10-01T02:29:44.127411] Saving JSON to bench_final/run1/medmcqa/medmcqa_1060/pi_iteration_3_tool_result_2_hybrid_search.json
[2025-10-01T02:29:44.169575] [PI] Continuing reasoning with 1 function responses...
[2025-10-01T02:29:50.859869] [PI] Reasoning iteration 4
[2025-10-01T02:29:50.861498] [PI] No function calls found in response
[2025-10-01T02:29:50.864666] [PI] No more function calls - research complete
[2025-10-01T02:29:50.866960] Saving text to bench_final/run1/medmcqa/medmcqa_1060/pi_final_answer.txt
[2025-10-01T02:29:50.886481] [QUERYOME] Query completed successfully
