PPI-Surfer: A protein-protein interface comparison program based on local surface matching


PPI-Surfer is a protein-protein interface comparison program that uses local surface matching between the PPIs. It uses three-dimensional Zernike descriptor to calculate similarity of the patches. Detailed description of the program is given in the reference below:

  • W.-H. Shin, K. Kumazawa, K. Imai, H. Takatsugu, and D. Kihara*, Quantitative Comparison of Protein-Protein Interaction Interface Using Physico-Chemical Feature-Based Descriptors of Surface Patches, Front. Mol. Biosci. Submitted.


    Binary executible files, running python scripts, and example can be freely downloadable at the following link.

    PPI-Surfer

    Contact Information

    If you have any questions or suggestions, please feel free to contact us (dkihara@purdue.edu).